Skin Barriere and Immune Response Related Biomarkers of Solar UVR Exposure Comparing Indoor and Outdoor Workers

Scientific Publications

Skin Barriere and Immune Response Related Biomarkers of Solar UVR Exposure Comparing Indoor and Outdoor Workers

JID Innovations Volume 4, Issue 3100280, May 2024

Outdoor workers are at higher risk for skin cancer due to long-term sun (UV) exposure. This study tested whether noninvasive skin biomarkers could detect this chronic damage. Researchers sampled the outermost skin layer from the forehead (high sun exposure) and behind the ear (low exposure) in both indoor and outdoor workers. They examined immune markers and skin barrier features, including Loretta’s AI-analyzed nanoscale corneocyte images. The results revealed clear differences: forehead skin showed stronger UV-related changes, and outdoor workers had more overall sun impact. This proves Loretta’s nanoscale topography is a reliable way to assess UV damage, helping prevent skin issues early.

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